| ￥1200 | |
| A03108-50 | |
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| Specificity | This product is specific to Topoisomerase 1 |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human Topoisomerase 1 |
| Species Reactivity | Human; Mouse |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
All lanes use the Topoisomerase 1 Antibody, mAb, Rabbit at 1:2K dilution for 1 hour at room temperature. »
| Target Background | Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. |
| Synonyms | DNA topoisomerase 1; DNA topoisomerase I; TOP1; TOPI; topoisomerase I; type I DNA |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
