ToxinEraser™ Endotoxin Removal Kit
| ¥1200 | |
| L00338 | |
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TM Endotoxin Removal Kit, endotoxin removal, endotoxin removal resin, remove endotoxin">
| ¥1200 | |
| L00338 | |
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| Product Description | GenScript’s ToxinEraser™ is an endototoxin removal resin of high efficiency. It is based on affinity matrix of modified polymyxin B (PMB), which allows highly efficient endotoxin removal. The final endotoxin level can be decreased to less than 0.1 EU/ml with repeated use of ToxinEraser™ endotoxin removal resin. Final removal efficiency may vary depending on the sample type/source. | ||||||||||||||||
| Key Features |
● High stability and high removal efficiency ● High binding capacity: > 2,000,000 EU/ml settled resin ● Fast flow without any constant speed pump ● Reusable up to five times if properly regenerated ● Ready-to-use reagents and materials, such as equilibration and regeneration buffers, collection tubes, etc. |
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| Size | 1.5 ml in pre-packed column | ||||||||||||||||
| Binding capacity | Up to 2,000,000 EU/ml resin | ||||||||||||||||
| Ligand | Modified PMB (Polymixin B) | ||||||||||||||||
| pH Stability | pH 5-10 | ||||||||||||||||
| Support Matrix | 4% cross-linked agarose, spherical beads | ||||||||||||||||
| Mean Particle Size | 90 μm | ||||||||||||||||
| Equilibration Buffer | Sodium Phosphate-Buffer, pH 8.0 | ||||||||||||||||
| Regeneration Buffer | Sodium Phosphate-Buffer, pH 8.0; Triton-114 | ||||||||||||||||
| Targets Suitable for Purification | Purified recombinant proteins, peptides, antibodies, polysaccharides, etc. | ||||||||||||||||
| Tolerable Ionic Strength | 0.1-0.5 M NaCl | ||||||||||||||||
| Performance-compatible Reagents | 20% DMSO, 20% ethanol, 20% glycerol;1 M urea, 300 mM imidazole; 0.05% Tween 20, 10 mM DTT. | ||||||||||||||||
| Storage | 2°C to 8°C (Do not freeze.) | ||||||||||||||||
| Kit Contents |
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The Effect of pH on Removal Efficiency
Fig. 1. Endotoxin removal can be performed in solutions from pH 5 -10 but the highest removal efficiency occurs at pH 7-8. The removal efficiency decreases upon deviation from neutral pH.
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The Effect of Endotoxin Concentration on Removal Efficiency
Fig. 2. Endotoxin removal efficiency is highly affected by and directly proportional to endotoxin concentration.
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.