IL-22[Biotin], His & Avi, Mouse
| ¥5800 | |
| Z04670-100 | |
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| ¥5800 | |
| Z04670-100 | |
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| Species | Mouse | ||||||
| Protein Construction |
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| Conjugate | Biotin | ||||||
| Purity | > 95% as determined by BisTris PAGE | ||||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||||
| Biological Activity | Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch. | ||||||
| Expression System | E.coli | ||||||
| Theoretical Molecular Weight | 19.7 kDa | ||||||
| Apparent Molecular Weight | The protein has a predicted MW of 19.7 kDa same as Bis-Tris PAGE result. | ||||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). | ||||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Loaded Mouse IL-22R alpha 1, hFc Tag on ProA-Biosensor can bindIL-22[Biotin], His & Avi, Mouse, His-Avi Tag with an affinity constant of 13.50 nM as determined in BLI assay (Gator® Prime). »
Immobilized IL-22[Biotin], His & Avi, Mouse, His Tag at 2 μg/ml (100 μl/well) on the streptavidin precoated plate(5 μg/ml). Dose response curve for Mouse IL-22R alpha 1, hFc Tag with the EC50 of 14.8ng/ml determined by ELISA. »
The purity of IL-22[Biotin], His & Avi, Mouse is greater than 90% as determined by SEC-HPLC. »
IL-22[Biotin], His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
IL-22[Biotin], His & Avi, Mouse, His Tag immobilized on CM5 Chip can bind Biotinylated Mouse IL-22, His Tag with an affinity constant of 0.145 μM as determined in SPR assay (Biacore T200). »
| Target Background | The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. |
| Synonyms | Interleukin-22; IL-22; Cytokine Zcyto18; IL-TIF; IL-D110; TIFa; TIFIL-23; ZCYTO18 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.