| ￥3300 | |
| Z05440-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 23.8 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 26-28 kDa&30-32 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized IL-15RA&IL-15, His, Human, His Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Human IL-2 R beta&IL-2 R gamma, hFc Tag with the EC50 of 39.8ng/ml determined by ELISA. »
The purity of IL-15RA&IL-15, His, Human is greater than 95% as determined by SEC-HPLC. »
IL-15RA&IL-15, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
Human IL-2 R beta&IL-2 R gamma, hFc Tag captured on CM5 Chip via Protein A can bind IL-15RA&IL-15, His, Human, His Tag with an affinity constant of 0.084 nM as determined in SPR assay (Biacore T200). »
| Target Background | Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development. |
| Synonyms | IL-15 R alpha;CD215;IL15RA;IL-15RA;IL-15R-alpha1;Interleukin-15;IL-15;IL15; Nanrilkefusp alfa |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
