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Teleost GSDMEc regulates GSDMEa-mediated pyroptos
Authors: Hang Xu, Meng Wu, Yujian Wang, Yaoming Jiao, Yuan Chen, Zihao Yuan, Li Sun
Journal: J Adv Res
PubMed ID: 40210150
Doi: doi.org/10.1016/j.jare.2025.04.007
Phosphorylation dependent charge block regulate the relaxation of nuclear speckle networks
Authors: Mengjun Zhang, Zhuang Gu, Yingtian Sun, Yichen Dong, Junlin Chen, Li Shu, Suibin Ma, Jierui Guo, Yuhang Liang, Qingming Qu, Ning Fang, Chuan-Qi Zhong, Yifan Ge, Zhongwen Chen, Shaohui Huang, Xin Zhang, Bo Wang
Journal: Mol Cell
PubMed ID: 40233760
Doi: 10.1016/j.molcel.2025.03.016
N-Terminal random curl-tandam α-helical peptide 7W: A potent antibacterial and anti-inflammatory dual-effect agent through tryptophan substitution
Authors: Jietao Lou, Xinyi Wu, Wenwen Ji, Jiaye Yu, Yanyan Xu, Wanyang Xiao, Weijie Lu, Kaiyun Xin, Tianbao Chen, Qidong Tang, Guang Liang, Yitian Gao, Di Wu
Journal: Eur J Med Chem
PubMed ID: 40319576
Doi: 10.1016/j.ejmech.2025.117686
Products & Services: Peptide Synthesis   
Targeted Delivery of mRNA with Polymer−Lipid Nanoparticles for In Vivo Base Editing
Authors: Qimingxing Chen, Yan Chang, Xiaoyan He, Yan Ding, Runyuan Wang, Ran Luo, Jialu Yuan, Jiabei Chen, Guisheng Zhong, Huiying Yang, Jia Chen, Jianfeng Li
Journal: ACS Nano
PubMed ID: 39962883
Doi: 10.1021/acsnano.4c14041
Fullerol Initiates Stem Cell–Nanomaterials Interactions for Enhanced Tissue Regeneration via Clathrin-Mediated Endocytosis and Nuclear Factor Erythroid 2-Related Factor 2 Signaling
Authors: Haoyang Liu, Yue Zhu, Weixu Chen, Renwang Sheng, Chuanquan Liu, Yuzhi Sun, Jia Liu, Mingyue Wang, Jun Lu, Jialin Chen, Wei Zhang
Journal: ACS Applied Materials & Interfaces
Doi: 10.1021/acsami.5c01731
Products & Services: Recombinant Proteins   
PIN1-SUMO2/3 motif suppresses excessive RNF168 chromatin accumulation and ubiquitin signaling to promote IR resistance
Authors: Anoop S Chauhan, Matthew J W Mackintosh, Joseph Cassar, Alexander J Lanz, Mohammed Jamshad, Hannah L Mackay, Alexander J Garvin, Alexandra K Walker, Satpal S Jhujh, Teresa Carlomagno, Aneika C Leney, Grant S Stewart, Joanna R Morris
Journal: Nature Communication
PubMed ID: 40229270
Doi: 10.1038/s41467-025-56974-9
Products & Services: Peptide Synthesis   Monoclonal Antibody Services   
Inhibitor-based modulation of huntingtin aggregation mechanisms mitigates fibrilinduced cellular stress
Authors: Greeshma Jain, Marina Trombetta-Lima, Irina Matlahov, Hennrique Taborda Ribas, Tingting Chen, Raffaella Parlato, Giuseppe Portale, Amalia M. Dolga & Patrick C. A. van der Wel
Journal: Nat Commun
PubMed ID: 40234398
Doi: 10.1038/s41467-025-58691-9
Products & Services: Plasmid DNA Preparation   Catalog Antibody   
Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease
Authors: Emre Fertan; Jeff Y. L. Lam; Giulia Albertini; Maarten Dewilde; Yunzhao Wu; Oluwatomi E. S. Akingbade; Dorothea B ken; Elizabeth A. English; Bart De Strooper; David Klenerman
Journal: Alzheimer's & Dementia
PubMed ID: 40237235
Doi: 10.1002/alz.70086
Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration
Authors: Zhuo Li, Zhengnan Guo, Zhengmeng Yang, Boguang Yang, Yuan Hu, Xian Xie, Zhixian Zong, Zekun Chen, Kunyu Zhang, Pengchao Zhao, Gang Li, Xuefeng Yang, Liming Bian
Journal: Cell Rep
PubMed ID: 40272981
Doi: 10.1016/j.celrep.2025.115611
Products & Services: Peptide Synthesis   
Inhibiting Chemotherapy Immune Tolerance and Reversing Tumor Microenvironment by Macrophage-Targeted Nanohybrid Systems for Enhancing Tumor Chemo-Immunotherapy
Authors: You-Teng Qin, Zhi-Yong Rao, Jia-Xin An, Shi-Man Zhang, Yu-Zhang Wang, Ting Pan, and Xian-Zheng Zhang
Journal: Advanced Functional Materials
Doi: doi.org/10.1002/adfm.202501954
Products & Services: Recombinant Proteins   
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