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Amelioration of Posttraumatic Osteoarthritis in Mice Using Intraarticular Silencing of Periostin via Nanoparticle-Based Small Interfering RNA
Authors: Xin Duan, Lei Cai, Christine T N Pham, Yousef Abu-Amer, Hua Pan, Robert H Brophy, Samuel A Wickline, Muhammad Farooq Rai
Journal: Arthritis Rheumatol
PubMed ID: 33982891
Doi: 10.1002/art.41794
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Effect on Osteogenic Differentiation of Genetically Modified IL4 or PDGF-BB Over-Expressing and IL4-PDGF-BB Co-Over-Expressing Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro
Authors: Masanori Tsubosaka, Masahiro Maruyama, Elijah Ejun Huang, Ning Zhang, Takeshi Utsunomiya, Qi Gao, Huaishuang Shen, Xueping Li, Junichi Kushioka, Hirohito Hirata, Zhenyu Yao, Yunzhi Peter Yang, Stuart B Goodman
Journal: Bioengineering (Basel)
PubMed ID: 34821731
Doi: 10.3390/bioengineering8110165
Products & Services: Gene Fragments   
Key substitutions in the spike protein of SARS-CoV-2 variants can predict resistance to monoclonal antibodies, but other substitutions can modify the effects
Authors: Sabrina Lusvarghi, Wei Wang, Rachel Herrup, Sabari Nath Neerukonda, Russell Vassell, Lisa Bentley, Ann E Eakin, Karl J Erlandson, Carol D Weiss
Journal: J Virol
PubMed ID: 34668774
Doi: 10.1128/JVI.01110-21
Products & Services: Plasmid DNA Preparation   
The glycan hole area of HIV-1 envelope trimers contributes prominently to the induction of autologous neutralization
Authors: Anna Schorcht, Christopher A Cottrell, Pavel Pugach, Rajesh P Ringe, Alvin X Han, Joel D Allen, Tom L G M van den Kerkhof, Gemma E Seabright, Edith E Schermer, Thomas J Ketas, Judith A Burger, Jelle van Schooten, Celia C LaBranche, Gabriel Ozorowski, Natalia de Val, Daniel L V Bader, Hanneke Schuitemaker, Colin A Russell, David C Montefiori, Marit J van Gils, Max Crispin, P J Klasse, Andrew B Ward, John P Moore, Rogier W Sanders
Journal: J Virol
PubMed ID: 34669426
Doi: 10.1128/JVI.01552-21
Products & Services: Codon Optimization   
A dedicated flavin-dependent monooxygenase catalyzes the hydroxylation of demethoxyubiquinone into ubiquinone (coenzyme Q) in Arabidopsis
Authors: Scott Latimer, Shea A Keene, Lauren R Stutts, Antoine Berger, Ann C Bernert, Eric Soubeyrand, Janet Wright, Catherine F Clarke, Anna K Block, Thomas A Colquhoun, Christian Elowsky, Alan Christensen, Mark A Wilson, Gilles J Basset
Journal: J Biol Chem
PubMed ID: 34626646
Doi: 10.1016/j.jbc.2021.101283
Products & Services: Gene Synthesis   
Minimalistic mycoplasmas harbor different functional toxin-antitoxin systems
Authors: Virginia Hill, Hatice Akarsu, Rubén Sánchez Barbarroja, Valentina L Cippà, Peter Kuhnert, Martin Heller, Laurent Falquet, Manfred Heller, Michael H Stoffel, Fabien Labroussaa, Joerg Jores
Journal: PLoS Genet
PubMed ID: 34673769
Doi: 10.1371/journal.pgen.1009365
Products & Services: Catalog Antibodies   
The intrinsic kinase activity of BRD4 spans its BD2-B-BID domains
Authors: Jocelyn D Weissman, Amit K Singh, Ballachanda N Devaiah, Peter Schuck, Ross C LaRue, Dinah S Singer
Journal: J Biol Chem
PubMed ID: 34688663
Doi: 10.1016/j.jbc.2021.101326
Products & Services: Protein and Antibody Isolation   
Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases
Authors: Xiaojie Chu, Zehua Sun, Du-San Baek, Wei Li, John W Mellors, Steven D Shapiro, Dimiter S Dimitrov
Journal: Int J Mol Sci
PubMed ID: 34681796
Doi: 10.3390/ijms222011136
Products & Services: Plasmid DNA Preparation   
A New Hybrid Protein Is a Novel Regulator for Experimental Colitis in Rats
Authors: Kohki Okada, Masaki Ikemoto
Journal: Inflammation
PubMed ID: 34628574
Doi: 10.1007/s10753-021-01537-5
Products & Services: Protein and Antibody Isolation   
Characterization of a P-glycoprotein drug transporter from Toxocara canis with a novel pharmacological profile
Authors: Jeba R J Jesudoss Chelladurai, Douglas E Jones, Matthew T Brewer
Journal: Int J Parasitol Drugs Drug Resist
PubMed ID: 34753107
Doi: 10.1016/j.ijpddr.2021.10.002
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