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Inhibitor-based modulation of huntingtin aggregation mechanisms mitigates fibrilinduced cellular stress
Authors: Greeshma Jain, Marina Trombetta-Lima, Irina Matlahov, Hennrique Taborda Ribas, Tingting Chen, Raffaella Parlato, Giuseppe Portale, Amalia M. Dolga & Patrick C. A. van der Wel
Journal: Nat Commun
PubMed ID: 40234398
Doi: 10.1038/s41467-025-58691-9
Products & Services: Plasmid DNA Preparation   Catalog Antibody   
Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease
Authors: Emre Fertan; Jeff Y. L. Lam; Giulia Albertini; Maarten Dewilde; Yunzhao Wu; Oluwatomi E. S. Akingbade; Dorothea B ken; Elizabeth A. English; Bart De Strooper; David Klenerman
Journal: Alzheimer's & Dementia
PubMed ID: 40237235
Doi: 10.1002/alz.70086
Products & Services: Proteins, Expression, Isolation and Analysis   
Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration
Authors: Zhuo Li, Zhengnan Guo, Zhengmeng Yang, Boguang Yang, Yuan Hu, Xian Xie, Zhixian Zong, Zekun Chen, Kunyu Zhang, Pengchao Zhao, Gang Li, Xuefeng Yang, Liming Bian
Journal: Cell Rep
PubMed ID: 40272981
Doi: 10.1016/j.celrep.2025.115611
Products & Services: Peptide Synthesis   
Inhibiting Chemotherapy Immune Tolerance and Reversing Tumor Microenvironment by Macrophage-Targeted Nanohybrid Systems for Enhancing Tumor Chemo-Immunotherapy
Authors: You-Teng Qin, Zhi-Yong Rao, Jia-Xin An, Shi-Man Zhang, Yu-Zhang Wang, Ting Pan, and Xian-Zheng Zhang
Journal: Advanced Functional Materials
Doi: doi.org/10.1002/adfm.202501954
Products & Services: Recombinant Proteins   
Synergistic impact of macrolide resistance and H3N2 infection on M. pneumoniae outbreak in children
Authors: Jiali Chen, Yingdan Wang, Juan Cheng, Yunping Ma, Xin Zhang, Xuezhou Bai, Palizhati Rehati, Huashun Cui, Fan Wu, Qiuhui Pan, Jinghe Huang
Journal: Microbiology Spectrum
PubMed ID: 39998323
Doi: 10.1128/spectrum.01844-24
Products & Services: Gene Synthesis   
The PYRIN domain is required for TLR4-mediated inflammation by PYHIN family members
Authors: Andrea Iannucci, Davide Lacarbonara, Valeria Caneparo, Federica Castiglioni, Andrea Butticè, Stefano Raviola, Chiara Porta, Riccardo Miggiano, Ivan Zanoni, Marisa Gariglio, Marco De Andrea
Journal: iScience
PubMed ID: 40454096
Doi: 10.1016/j.isci.2025.112413
Products & Services: Mutagenesis Services   
Molecular mechanisms of the viral encoded chaperone 100K in capsid folding and assembly of adenovirus
Authors: Haining Li , Luyuan Shao , Zhe Liu , Qi Liu , Ye Xiang
Journal: Nat Commun
PubMed ID: 40301360
Doi: 10.1038/s41467-025-59301-4
Products & Services: Proteins, Expression, Isolation and Analysis   
Molecular determinants for the association of human hormone-sensitive lipase with lipid droplets
Authors: Han Peng, Qikui Xu, Ting Zhang, Jiakai Zhu, Jinheng Pan, Xiaoyu Guan, Shan Feng, Jianping Wu, Qi Hu
Journal: Nature Communication
PubMed ID: 40221426
Doi: 10.1038/s41467-025-58887-z
Products & Services: Proteins, Expression, Isolation and Analysis   
The Atypical Pectin Methylesterase Family Member PME31 Promotes Seedling Lipid Droplet Utilization
Authors: Sarah Hamade, Melissa S Traver , Bonnie Bartel
Journal: Plant Direct
PubMed ID: 40212536
Doi: doi.org/10.1002/pld3.70054
Products & Services: Catalog Antibody   
Nanosized Shikonin Disrupts Tumor-cell Mismatch Repair and Synergizes with Manganese to Sensitize Squamous Carcinoma to Immunotherapy
Authors: Shan Yu, Jingyuan Li, Jie Zhang, Guozhong Zeng, Bin Zeng, Shuyuan Song, Zhentao Lao, Haolin Chen, Zhenfu Wen, Zeyu Yang, Xiang Li, Kan Li, Le Yang, Hong Liu, Lixin Liu, Guiqing Liao, Yongming Chen, Yujie Liang
Journal: ACS Nano
PubMed ID: 40190094
Doi: 10.1021/acsnano.4c17090.
Products & Services: Proteins, Expression, Isolation and Analysis